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The primary objective of the Jackson Heart Study is to investigate the causes of cardiovascular disease (CVD) in African Americans to learn how to best prevent this group of diseases in the future.

Specific objectives include:
Identification of factors, which influence the development, and worsening of CVD in African Americans, with an emphasis on manifestations related to high blood pressure (such as remodeling of the left ventricle of the heart, coronary artery disease, heart failure, stroke, and disorders affecting the blood vessels of the kidney).
Building research capabilities in minority institutions at the undergraduate and graduate level by developing partnerships between minority and majority institutions and enhancing participation of minority investigators in large-scale epidemiologic studies.
Attracting minority students to and preparing them for careers in health sciences.

The Jackson Heart Study conducted three cohort examinations, an initial clinic examination from 2000 to 2004 (Exam1), followed by a second exam from 2005 to 2008 (Exam 2) and a final exam in 2009 to 2013 (Exam 3). Starting in 2001, participants have been contacted annually, and ascertainment of hospitalizations for cardiovascular events and deaths is ongoing.

The Longitudinal Study of Generations (LSOG), initiated in 1971, began as a survey of intergenerational relations among 300 three-generation California families with grandparents (then in their sixties), middle-aged parents (then in their early forties), and grandchildren (then aged 15 to 26). The study broadened in 1991 and now includes a fourth generation, the great-grandchildren of these same families.

The study objectives were:

To track life-course trajectories of family intergenerational solidarity and conflict over three decades of adulthood, and across successive generations of family members;
To identify how intergenerational solidarity and conflict influence the well-being of family members throughout the adult life-course and across successive generations;
To chart the effects of socio-historical change on families, intergenerational relationships, and individual life-course development during the past three decades;
To examine women’s roles and relationships in multigenerational families over 30 years of rapid change in the social trajectories of women’s lives.

Convenience sample of centenarians, their siblings, offspring, spouses and a control sample consisting of people born around same time as offspring but who do not have parents surviving beyond average life expectancy for their birth cohort. Age range 40-119 years, with ~2500 centenarians in the sample including 600 semi-supercentenarians (ages 105-109) and 200 supercentenarians (ages 110+ years).

We collect the below listed data at enrolment and then collect vital status, hospitalization, changes in meds and diagnoses, cognitive function (TICS) and physical function (IADS, ADL) over the phone, annually. Local subjects are asked to undergo annual detailed cognitive function testing in person with ultimately, brain donation. Blood sample collected at enrolment for DNA, RNA and plasma for biomarkers and storage.

Study is open to collaborations. Please contact Dr. Perls

The Nurses’ Health Study is a longitudinal population study aimed initially to examine the relation between the use of oral contraceptives, cigarette smoking, and risk of major illnesses in women, mainly cancer and cardiovascular diseases. Since then, the study broadened to include the evaluation of health consequences of many lifestyle practices, including diet, physical activity, and specific forms of hormone therapy.

The participants are registered nurses, aged 30 to 55 years and married at the time of recruitment in 1976, and who lived in the 11 most populous states (California, Connecticut, Florida, Maryland, Massachusetts, Michigan, New Jersey, New York, Ohio, Pennsylvania and Texas).

The NLSY 1979 Cohort is a longitudinal project that follows the lives of 12,686 American youth born between 1957 and 1964. The study was intended to be representative of United States residents, both male and female. It observes the life-course experiences of young adults who were finishing their schooling and were making decisions about education and training, entering the labour market, military service, marriage, and having families. Cohort members are now in their 50s and survey content has turned to age-appropriate topics including health and retirement expectations.

Yearly personal interviews were conducted from 1979 – 1986. In 1987, a telephone interview was conducted. Personal interviews resumed in 1988 and continued yearly until 1994. Since 1994, NLSY79 participants have been interviewed in even-numbered years.

In 1999 the Swedish Ministry for Social Affairs promoted and supported a national project aimed at monitoring and evaluating the care-of-the-elderly system in Sweden. To achieve these aims, four longitudinal individual-based data collection describing the aging process and encompassing the care system as whole, has been initiated. This project was named The Swedish National study on Aging and Care (SNAC).

SNAC-K is conducted by the Stockholm Gerontology Research Center in collaboration with Aging Research Center (ARC), Karolinska Institutet.

SNAC-K includes two studies: SNAC-K population study and SNAC-K care system study.

The Stockholm Birth Cohort Study (SBC) was created in 2004/2005 by a probability matching of two comprehensive and longitudinal datasets. The first, the Stockholm Metropolitan study 19531985, consists of all children born in 1953 and living in the Stockholm metropolitan area in 1963. The second, The Swedish Work and Mortality Database 19802009 (WMD), consists of all individuals living in Sweden in 1980 or 1990, and born before 1985. The initiative to create the database was taken by Denny Vågerö at the Centre for Health Equity Studies, CHESS, of Stockholm University/Karolinska Institute and Sten-Åke Stenberg at the Swedish Institute for Social Research, Stockholm University (SOFI). The resulting database provides a 50-year long follow-up of the original 1953 birth cohort.

The Kungsholmen Project is a longitudinal population-based study on ageing and dementia, carried out by the Stockholm Gerontology Research Center in collaboration with Aging Research Center (ARC), Karolinska Institutet.

The project, which started in 1987, has gathered a 12-year long database and offers information on aging from a multidisciplinary perspective. All persons that were born before 1913 and lived in the Kungsholmen district of Stockholm, were invited to participate (a total of 2368 persons on October 1st, 1987, including both community-dwelling and institutionalized persons). Later, the research additionally included all 90+ old subjects living in the St. Göran parish, an adjacent geographical area. The baseline phase and four follow-ups have been completed, with the last phase concluding in the summer of 2000. Time 1 was the only measurement occasion when a two-phase study design was adopted, with an extensive clinical examination performed after a screening phase. At every other occasion, all participants were interviewed by nurses, clinically examined by physicians, and assessed by psychologists.

The original study (1969-73) had five main objectives: (i) to study the relationship of birth weight (BW) and gestational age (GA) to infant mortality and the incidence of congenital defects; (ii) to study maternal blood pressure before and during pregnancy and the incidence of toxaemia; (iii) to assess the effects of parental consanguinity on reproductive outcomes; (iv) to examine the impact of family planning programmes on fertility and (v) to estimate rates of foetal loss, and neonatal, infant and early childhood mortality.1 The subsequent follow-up studies focused on the effects of prenatal factors BW and GA on physical growth and development and mortality during childhood and adolescence.

For the follow-up in young adulthood (1998-2002), the main objective was to study glucose tolerance, insulin resistance and insulin secretion and a range of cardiovascular risk factors (body composition, blood pressure and plasma lipid concentrations) in relation to parental size, neonatal size and childhood growth.

The Scottish Health Survey (SHeS) provides a detailed picture of the health of the Scottish population in private households and is designed to make a major contribution to the monitoring of health in Scotland.
The series aims to:
estimate the occurrence of particular health conditions
estimate the prevalence of certain risk factors associated with health
look at differences between regions and between subgroups of the population
monitor trends in the population’s health over time
make a major contribution to monitoring progress towards health targets