The ZARADEMP project (ZARAgoza DEMentia
DEPression project) was designed as a longitudinal,
community-based study to examine the incidence
of dementia and the risk factors in incident cases of
dementia. It was carried out in Zaragoza, a typical,
large city in Spain, with an important proportion
of inhabitants coming from surrounding rural
areas (12). A stratified random sample of individuals
55 years of age and older, with proportional
allocation by age and sex, drawn from the eligible
individuals (n = 157 787) in the Spanish official
census lists of 1991, was invited to participate in
the baseline examination.

The Atherosclerosis Risk in Communities Study (ARIC) is a prospective epidemiologic study conducted in four U.S. communities. ARIC is designed to investigate the etiology and natural history of atherosclerosis, the etiology of clinical atherosclerotic diseases, and variation in cardiovascular risk factors, medical care and disease by race, gender, location, and date. Since 2011 a large ancillary study, the ARIC Neurocognitive Study (ARIC-NCS) has been assessing neurocognitive status and adjudicating possible cases of dementia.

Four ARIC field centers each randomly selected and recruited a cohort sample of approximately 4,000 individuals aged 45-64 from a defined population in their community. A total of 15,792 participants received an extensive baseline examination (visit 1, 1987-1989), including medical, social, and demographic data collection. Subsequent examinations occurred in 1990-92 (visit 2), 1993-95 (visit 3), 1996-98 (visit 4), 2011-2013 (visit 5) and 2016-2017 (visit 6). Visit 7 (2018-2019) is currently in progress. Follow-up occurs annually (semi-annually since 2012) by telephone to maintain contact with participants and to assess health status of the cohort.

The West of Scotland Twenty-07 Study: ‘Health in the community’ was set up in 1986 in order to investigate the reasons for differences in health by socio-economic circumstances, gender, the place where people live, age, ethnic group and family type.

The basic design of the Study involved recruiting three cohorts (groups) of volunteers, each group born twenty years apart. Members of the oldest cohort were born around 1932, those in the middle cohort were born in 1952, and those in the youngest cohort were born in 1972. A total of 4,510 people agreed to take part, and have been followed for 20 years. The final wave of data collection was completed in 2008. This means that when the Study began (1987/8) participants were 15, 35 or 55 years old, and by the end of the Study (2007/8), participants were 35, 55 and 75 years old.
The data collected are extensive and include self-reported mental and physical health (including chronic conditions, medications, disabilities); physical measures; biomarkers; cognition; life circumstances (including employment, housing, family); health behaviours; beliefs, attitudes and values. The cohort is being followed up for mortality using linkage to national records. Any data on neurodegenerative disease are from self-reported health and / or death certificates.
A full description of the cohort profile is available in the following publication: Cohort Profile: West of Scotland 20-07 study: health in the community. International Journal of Epidemiology 2009;38:1215-23

The Concord Health and Ageing in Men Project (CHAMP) is one of the world’s largest and most comprehensive study of the health of older men ever conducted anywhere in the world. CHAMP involves 1705 men aged 70 years and older recruited from the community living near Concord Hospital in Sydney’s inner west. Subjects were recruited during 2005 and 2006 and subjects were re-assessed after two, five and nine years. A 14 year follow-up assessment (wave 5) is planned for 2019. Clinical dementia assessment was done at baseline but not in waves 2, 3, and 4. Clinical dementia assessment will be included in wave 5.

The study is particularly concerned with cognitive impairment and dementia; falls, fractures and osteoporosis; and urinary problems.

The VLS is a long-term, large-scale, and multi-faceted longitudinal investigation of human aging. Incorporating biomedical approaches, leading-edge technologies, and epidemiological perspectives, the VLS evaluates and tracks actual cognitive, health, functional and lifestyle trajectories leading to outcomes that can be classified as normal, resilient, exceptional, impaired, or dementia. Our studies examine these differential brain and cognitive changes as a function of interactions among multiple “biomarkers” of both risk and protection. Among these dynamically interacting biomarkers are those representing selected aspects of biological, health, genetic, metabolic, vascular, lifestyle, physical fitness, cognitive activity, sex/gender, and demographic domains

Korea became an ageing society in 2000, as the proportion of those 65 or older reached 7% of the population. Thereafter, the country is expected to undergo a rapid ageing process. Korea was belated compared to other advanced countries in reaching the ageing society status, but it is expected to become a super-aged society around the same time as others.

Lacking in basic data on ageing, Korea is in need of a structured set of statistical data. – Institutional reform and policy-making in preparation against the aged society require systematic build-up of data that can track individuals’ labor participation, income and asset status, spending patterns, retirement decisions, impact of social welfare, health, and intra-family transfer of income, among others.

The purpose of KLoSA is to create the basic data needed to devise and implement effective social, economic policies to address the trends that emerge in the process of population ageing.

The data will help identify and observe different dimensions of an aged society, build datasets that enable studies in different fields, and generate data comparable with similar panel studies in other countries (eg. U.S., Europe) that can provide the basis for policy-making and academic studies.

The Confucius Hometown Aging Project (CHAP) is a longitudinal study of vascular risk factors, ageing, and health in people aged 60 years or older who live in a rural community near Qufu (hometown of Confucius), Shandong, China. The study was done by local hospital staff consisting of clinicians and nurses.

JSTAR project researchers aimed to construct a world-class longitudinal dataset on middle-aged and elderly Japanese persons to enable researchers worldwide to perform scientific investigation on aging and retirement from an international perspective. Despite the rapid aging of the Japanese population, no statistical survey that could properly capture the diversity of the elderly population from various viewpoints had been carried out in Japan until recently. RIETI, Hitotsubashi University jointly launched a comprehensive survey of elderly people in 2007 to collect panel data on their lives and health, with the University of Tokyo joining from 2009 onward.
The 2009 JSTAR survey includes a follow-up survey of the respondents to the 2007 survey and an initial survey of elderly people in two additional municipalities, i.e., Tosu in Saga Prefecture and Naha in Okinawa Prefecture, whereas the 2011 JSTAR Survey includes follow-up surveys of the respondents to the 2007 and 2009 surveys plus an initial survey of elderly people in three additional municipalities, Tondabayashi, Chofu, and Hiroshima

The EPIPorto study is a landmark in epidemiological research in Portugal. It is a population-based cohort study, ongoing for over 15 years, with the main aim of assessing the determinants of health in the adult population of Porto. For this purpose we randomly selected 2485 persons, who have been repeatedly evaluated over time.

Participants were invited to visit the study centre to answer a questionnaire on social, demographic and behavioural characteristics, and their clinical history. Additionally, objective measurements were made, including blood tests, blood pressure, weight and height, electrocardiogram, evaluation of lung function and bone mineral density. The participants’ address was georeferenced, allowing the analysis of the spatial distribution of health states and events in the city. Subgroups of the cohort at the baseline evaluation were used as controls in case-control studies namely on myocardial infarction and gastric cancer.

The National Child Development Study (NCDS) is a longitudinal study which follows the lives of 17,000 people born in England, Scotland and Wales in a single week of 1958. Also known as the 1958 Birth Cohort Study, it collects information on physical and educational development, economic circumstances, employment, family life, health behaviour, wellbeing, social participation and attitudes.

Since the birth survey in 1958, there have been nine further ‘sweeps’ of all cohort members at ages 7, 11, 16, 23, 33, 42, 46, 50 and 55. In 2003 (at age 45), 9,000 cohort members also participated in a special bio-medical survey to learn more about how development, environments and lifestyles affect people’s health. CLS will carry out a new survey of the NCDS cohort at age 60 in 2018.

NCDS is part of CLOSER (Cohort & Longitudinal Studies Enhancement Resources) which aims to maximise the use, value and impact of the UK’s longitudinal studies.