Export as PDF
Cohort Acronym
VP-EDAD

Cohort type
Neurodegenerative disease-specific cohort

Disease
Alzheimer's disease, Dementia (unclassified), Mild cognitive impairment (MCI), Subjective memory complaints (SMC) or subjective cognitive decline (SCD), Vascular dementia

Participant type
At-risk diagnosis

Profile
Recruitment Period 2011 
Sample size at start or planned sample size if still recruiting 1213  
Estimated Current Sample Size 1169 
Age at Recruitment 70-85   
Gender Male and Female 
Abstract

The Vallecas Project is developed in the Research Unit of the Alzheimer’s Center of the Reina Sofía Foundation by researchers of the CIEN Foundation. Its main objective is to determine a probabilistic algorithm for the identification of individuals at risk of dementia type Alzheimer’s disease (AD) in the course of a few years. This algorithm will be based on the combination of sociodemographic, clinical, neurological, neuropsychological, biological (from blood determinations) and neuroimaging (various 3 Tesla magnetic resonance modalities).

The recruitment phase of the Vallecas Project participants was extended from October 2011 to December 2013. Finally, a total of 1,213 volunteers aged between 70 and 85 and of both sexes were initially evaluated. Once included in the study, it is monitored annually for 5 years in order to assess the evolutionary profile of all participants, specifically identifying those who develop cognitive impairment and / or dementia. The cohort is being followed up annually for 4 years after the baseline.

 
Country Spain 
Contact details
Institution name Alzheimer center Queen Sofia Foundation (CIEN Foundation) 
Website http://www.fundacioncien.es/proyectos-de-investigacion/proyecto-vallecas 
Principal Investiator (PI) Miguel Medina 
Contact email Info@fundacioncien.es; gerencia@fundacioncien.es 
Contact phone number  
Address Alzheimer center Queen Sofia Foundation (CIEN Foundation)
C / Valderrebollo, 5
Centro Alzheimer Reina Sofía Foundation
Spain 
Funders (Core support) Queen Sofia Foundation; ISCIII 

Variables Collected

Brain related measures: Behaviour, Cognitive function, Mental health, Neurological
Funtional rating: Individual physiological, Individual psychological
Anthropometric: Blood pressure, Height, Hip circumference, Waist circumference, Weight
Physical: Cardiovascular, Hearing and Vision
Biological samples: Blood
Genotyping: Gene screening
Brain imaging: Magnetic resonance imaging (MRI)
Brain banking: Consent for brain donation
Lifestyle: Alcohol, Dietary habits, Physical activity, Smoking
Socio-economic: Education, Ethnic group, Family circumstances, Informal support, Marital status, Occupation and employment
Health service utilisation: Formal health and social care service utilisation including private care
 
Export as PDF