Comparison View

	The Atherosclerosis Risk in Communities Study	The ZARAgoza DEMentia DEPression project	EPIPorto	The 1970 British Cohort Study	Next Steps	The Malaysian Health and Adolescents Longitudinal Research Team study	LifeGene	Nurses’ Health Study (NHS) II	The Confucius Hometown Aging Project	1958 National Child Development Study
Cohort acronym	ARIC	ZARADEMP	EPIPorto	BCS70	Next Steps	MyHeART	LifeGene	NHSII	CHAP	NCDS
Cohort Type	General population-based cohort	General population-based cohort	General population-based cohort	General population-based cohort	General population-based cohort	General population-based cohort	General population-based cohort	General population-based cohort	General population-based cohort	General population-based cohort
Disease	Alzheimer's disease \| Mild cognitive impairment (MCI) \| Parkinson's disease \| Type of dementia/ND not specified \| Vascular dementia	Alzheimer's disease \| Dementia (unclassified) \| Mild cognitive impairment (MCI) \| Parkinson's disease \| Subjective memory complaints (SMC) or subjective cognitive decline (SCD) \| Vascular dementia	N/A	N/A	N/A	N/A	N/A	Mild cognitive impairment (MCI) \| Subjective memory complaints (SMC) or subjective cognitive decline (SCD)	N/A	N/A
Participant type	No diagnosis	At-risk diagnosis	N/A	No diagnosis	No diagnosis	No diagnosis	No diagnosis	No diagnosis	No diagnosis	No diagnosis
Recruitment period	1987-1989	1991	1999-2003	01/04/1970	2004	2012	N/A	1989	2010-2011	1958
Sample size at start	15,792	4,802	2,485	17,200	16,122	1,361	250,000	116,430	1,480	17,415
Estimated current sample size	7,400	1,500	N/A	9,841	15,629	N/A	52,107	N/A	850	9,790
Age at recruitment	45-64	>55	18-92	0	13-14	13	18-50	25-42	>60	0
Gender	Male and Female	Male and Female	Male and Female	Male and Female	Male and Female	Male and Female	Male and Female	Female	Male and Female	Male and Female
Abstract	ARIC is designed to investigate the etiology and natural history of atherosclerosis, the etiology of clinical atherosclerotic diseases, and variation in cardiovascular risk factors, medical care and disease by race, gender, location, and date.	The ZARADEMP project (ZARAgoza DEMentia DEPression project) was designed as a longitudinal, community-based study to examine the incidence of dementia and the risk factors in incident cases of dementia.	It is a population-based cohort study, ongoing for over 15 years, with the main aim of assessing the determinants of health in the adult population of Porto.	The 1970 British Cohort Study (BCS70) follows the lives of more than 17,000 people born in England, Scotland and Wales in a single week of 1970.	The study began in 2004 and included all young people in Year 9, aged between 13 and 14, who attended state and independent schools in England.	The MyHeART study is longitudinal cohort study of 1361 schoolchildren (13-years old) attending 15 public secondary schools from the central (Kuala Lumpur and Selangor) and northern (Perak) regions of Peninsular Malaysia	The study includes studying several hundred thousand Swedes with the aim of creating new tools to prevent, diagnose and treat our most common diseases.	The Nurses' Health Study II (NHS II) was established by Dr. Walter Willett and colleagues in 1989 with funding from the National Institutes of Health to study oral contraceptives, diet, and lifestyle risk factors in a population younger than the original NHS cohort.	The Confucius Hometown Aging Project (CHAP) is a longitudinal study of vascular risk factors, ageing, and health in people aged 60 years or older who live in a rural community near Qufu (hometown of Confucius), Shandong, China.	The National Child Development Study (NCDS) is a longitudinal study which follows the lives of 17,000 people born in England, Scotland and Wales in a single week of 1958.
Institute name	University of North Carolina at Chapel Hill	N/A	ISPUP - Public Health Institute of the University of Porto	University College, London	University College, London	University of Malaya	Karolinska Institutet	Brigham and Womens Hospital and Harvard School of Public Health	Jining Medical University	Centre for Longitudinal Studies
Website	http://www2.cscc.unc.edu/aric/	https://www.ncbi.nlm.nih.gov/pubmed/21848704	http://ispup.up.pt/research/research-structures/cohorts/	http://www.cls.ioe.ac.uk/page.aspx?&sitesectionid=795&sitesectiontitle=Welcome+to+the+1970+British+Cohort+Study	http://www.cls.ioe.ac.uk/page.aspx?&sitesectionid=1246&sitesectiontitle=Welcome+to+the+Longitudinal+Study+of+Young+People+in+England+	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251135/	https://www.lifegene.se/	http://www.nurseshealthstudy.org/	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895010/	http://www.cls.ioe.ac.uk/ncds
Principal investigator	Jacqueline Wright	Professor Antonio Lobo	Henrique Barros	Alice Sullivan	Dr Lisa Calderwood	Majid Abdul Hazreen	Nancy Pedersen	Heather Eliassen and Walter Willett	Chengxuan Qiu; Zhongrui Yan	Professor Alissa Goodman
Contact email	PI email: [email protected]; Contact email: [email protected]; [email protected]	[email protected]	[email protected]	[email protected]; PI email: [email protected]	[email protected]	[email protected]	[email protected]	[email protected]; PI email: [email protected]; [email protected]ning.harvard.edu	[email protected]	[email protected]
Contact phone number	919-962-3229; 919-962-3096	N/A	+351 222 061 820	44 (0) 2076126875	+44 (0)20 7612 6875	N/A	+46-8-524 874 18	617-525-2279	N/A	+44 (0)20 7612 6875
Address	ARIC Study Coordinating Center: PI: Dr. David Couper; Project Director: Ms. Kim Ring Collaborative Studies Coordinating Center Department of Biostatistics University of North Carolina at Chapel Hill 123 W. Franklin Street, Suite 450 Chapel Hill, NC 27516	Facultad de Medicina, Departamento de Medicina, Psiquiatría, C/ Domingo Miral s/n, 50009 Zaragoza, Spain	EPIUnit, Institute of Public Health, University of Porto, Porto, Portugal	Centre for Longitudinal Studies UCL Institute of Education 20 Bedford Way London WC1H 0AL	Centre for Longitudinal Studies	Centre for Population Health (CePH) and Department of Social & Preventive Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia	Director of LifeGene project and Professor in Genetic Epidemiology at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet	Nurses' Health Study II Channing Division of Network Medicine 181 Longwood Avenue Boston, MA 02115	Aging Research Center, Department of Neurobiology, Health Care Sciences and Society, Karolinska Institutet-Stockholm University, Stockholm, Sweden	Centre for Longitudinal Studies Institute of Education 20 Bedford Way London WC1H 0AL
Funders (core support)	National Institutes of Health (NIH)	Fondo de Investigación Sanitaria, Instituto de Salud Carlos III, Spanish Ministry of Health	Fundação para a Ciência e a Tecnologia (Foundation for Science and Technology)	Economic and Social Research Council.	Department of Education\|Economic and Social Research Council	N/A	Swedish Research Council\|Karolinska Institutet\|AFA Försäkring\|Ragnar and Torsten Söderberg's foundations	National Institute of Health (NIH)\|National Institute for Occupational Safety and Health (NIOSH)\|Breast Cancer Foundation	Department of Science and Technology and the Department of Health of Shandong Province, the Natural Science Foundation of Shandong Province	Economic and Social Research Council
Cognitive	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Functional Rating	Individual psychological	Individual psychological	Individual psychological	Individual psychological	Individual physiological \| Individual psychological	N/A	N/A	Individual physiological \| Individual psychological	Individual physiological \| Individual psychological	Individual physiological \| Individual psychological
Anthropometric	Blood pressure \| Height \| Hip circumference \| Waist circumference \| Weight	Blood pressure \| Height \| Weight	Blood pressure \| Height \| Hip circumference \| Waist circumference \| Weight	Blood pressure \| Height \| Hip circumference \| Waist circumference \| Weight	Height \| Weight	Blood pressure \| Height \| Hip circumference \| Waist circumference \| Weight	Blood pressure \| Height \| Hip circumference \| Waist circumference \| Weight	Blood pressure \| Height \| Hip circumference \| Waist circumference \| Weight	Blood pressure \| Height \| Waist circumference \| Weight	Blood pressure \| Height \| Hip circumference \| Waist circumference \| Weight
Physical	N/A	N/A	Cardiovascular \| Musculoskeletal \| Reproductive \| Respiratory	Cardiovascular \| Hearing and Vision \| Musculoskeletal \| Reproductive \| Respiratory	Hearing and Vision \| Reproductive	Musculoskeletal	Cardiovascular \| Hearing and Vision \| Musculoskeletal \| Reproductive \| Respiratory	Cardiovascular \| Hearing and Vision \| Musculoskeletal \| Reproductive \| Respiratory	Cardiovascular \| Hearing and Vision \| Musculoskeletal \| Reproductive \| Respiratory	Cardiovascular \| Hearing and Vision \| Musculoskeletal \| Reproductive \| Respiratory
Biological samples	Cardiovascular \| Hearing and vision \| Musculoskeletal \| Reproductive \| Respiratory	N/A	Blood	Blood	N/A	Blood	Blood \| Saliva	Blood \| Urine	Blood	Blood \| Saliva
Genotyping	Gene screening	N/A	N/A	N/A	N/A	N/A	Gene screening	Gene screening	N/A	Gene screening
Brain imaging	Magnetic resonance imaging (MRI) \| Positron emission tomography (PET) - amyloid	Magnetic resonance imaging (MRI)	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Brain banking	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Lifestyle	Alcohol \| Dietary habits \| Physical activity \| Smoking	Alcohol \| Physical activity \| Smoking	Alcohol \| Dietary habits \| Physical activity \| Smoking	Alcohol \| Dietary habits \| Physical activity \| Smoking	Alcohol \| Dietary habits \| Physical activity \| Smoking	Alcohol \| Dietary habits \| Physical activity \| Smoking	Alcohol \| Dietary habits \| Physical activity \| Smoking	Alcohol \| Dietary habits \| Physical activity \| Smoking	Alcohol \| Dietary habits \| Physical activity \| Smoking	Alcohol \| Dietary habits \| Physical activity \| Smoking
Socio-economic	Education \| Ethnic group \| Family circumstances \| Informal support \| Martial status \| Occupation and employment	Education \| Ethnic group \| Family circumstances \| Housing and accommodation \| Informal support \| Martial status \| Occupation and employment	Education \| Ethnic group \| Family circumstances \| Housing and accommodation \| Income and finances \| Informal support \| Martial status \| Occupation and employment \| Unpaid care	Education \| Ethnic group \| Family circumstances \| Housing and accommodation \| Income and finances \| Informal support \| Martial status \| Occupation and employment \| Unpaid care	Education \| Ethnic group \| Family circumstances \| Housing and accommodation \| Income and finances \| Informal support \| Martial status \| Occupation and employment \| Unpaid care	Ethnic group \| Family circumstances	Education \| Family circumstances \| Housing and accommodation \| Income and finances \| Martial status \| Occupation and employment	Ethnic group \| Housing and accommodation \| Informal support \| Martial status \| Occupation and employment	Education \| Ethnic group \| Family circumstances \| Housing and accommodation \| Income and finances \| Informal support \| Martial status \| Occupation and employment	Education \| Ethnic group \| Family circumstances \| Housing and accommodation \| Income and finances \| Informal support \| Martial status \| Occupation and employment \| Unpaid care
Health service utilisation	Formal health and social care service utilisation including private care	N/A	Formal health and social care service utilisation including private care	Formal health and social care service utilisation including private care	N/A	N/A	Formal health and social care service utilisation including private care	Formal health and social care service utilisation including private care	N/A	N/A
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