Name of resource

BRAINS Unit, Lund University

Name of Principal Investigator
Title Professor
First name Deniz
Last name Kirik
Address of institution where award is held
Institution Lund University
Street Address BMC D11
City Lund
Postcode 22184
Country
  • Sweden
  • Website

    http://www.med.lu.se/expmed/brains

    Contact email

    deniz.kirik@med.lu.se

    Summary

    We run a small vector production facility that makes high quality AAV vectors that we use to develop animal models of PD and HD.

    1a. The resource holds animal models relevant to the study of the following neurodegenerative diseases
  • Parkinson’s disease
  • Huntington’s disease
  • 1b. The resource holds:
  • Animals
  • Frozen embryos
  • Genetic material (DNA, RNA, vectors etc)
  • 2a. The resource acts as a centre for access and distribution to external groups (who are not the PIs of the resource)
    2b. Procedures and rules for access
  • Access through collaboration with PI only
  • 3a. Does the resource develop animal models for external groups

    1

    3b. Types of models provided
    4a This activity is supported as:
  • Independent of collaboration
  • 4b. The supplied material deposited in a central repository

    1

    5a Disease models available
    Disease Species Available to external user (Y/N) Full phenotypic character (Y/N or partial) Phenotypes Genotypes or other subtypes
    PD rat, mouse, primate partial partial DA cell loss alpha-synuclein
    HD rat, mouse partial partial metabolic dysfunction huntingtin
    5b. Other models/phenotypes available through the resource relevant to neurodegenerative conditions
    No. of models Available to external users Full phenotypic characterisation available (Y/N or partial) Nature of phenotype
    1 partial partial behavior and pathology
    2 partial partial behavior and pathology
    6. European or international consortia or networks to which the resource is linked
    Jackson Laboratories, USAInternational mouse knockout consortium
    Neugene
    MEFOPA
    Neurasyn
    7a. Maintenance of the resource is dependent on continued funding

    2

    7b. End date of current funding period

    2012-13

    7c. Expected lifespan of the resource (in years)

    2

    Types: Experimental Models
    Member States: Sweden
    Diseases: Huntington's disease, Parkinson's disease & PD-related disorders
    Years: 2011
    Database Categories: N/A
    Database Tags: N/A

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