Case-Control Study on Parkinson's Disease Among Mutualité Sociale Agricole Affliates in Five Départements
16 Avenue Paul Vaillant Couturier
ANR - ANSES - France Parkinson
To study the association of professional exposure to pesticides with Parkinson's disease and the role of gene-environment interactions
Study performed in farmers from five French regions. Population-based
1. Ahmed, I., P. C. Lee, C. M. Lill, S. Searles Nielsen, F. Artaud, L. G. Gallagher, M. A. Loriot, C. Mulot, M. Nacfer, T. Liu, J. M. Biernacka, S. Armasu, K. Anderson, F. M. Farin, C. F. Lassen, J. Hansen, J. H. Olsen, L. Bertram, D. M. Maraganore, H. Checkoway, B. Ritz and A. Elbaz (2014). "Lack of replication of the GRIN2A-by-coffee interaction in Parkinson disease." PLoS Genet 10(11): e1004788. 2. Ahmed, I., R. Tamouza, M. Delord, R. Krishnamoorthy, C. Tzourio, C. Mulot, M. Nacfer, J. C. Lambert, P. Beaune, P. L. Puig, M.-A. Loriot, D. Charron and A. Elbaz (2012). "Association between Parkinson's Disease and the HLA-DRB1 Locus." Mov Disord 27(9): 1104-1110. 3. Moisan, F., V. Gourlet, J. L. Mazurie, J. L. Dupupet, J. Houssinot, M. Goldberg, E. Imbernon, C. Tzourio and A. Elbaz (2011). "Prediction model of Parkinson's disease based on antiparkinsonian drug claims." Am J Epidemiol 174(3): 354-363. 4. Moisan, F., J. Spinosi, L. Delabre, V. Gourlet, J. L. Mazurie, I. Benatru, M. Goldberg, M. G. Weisskopf, E. Imbernon, C. Tzourio and A. Elbaz (2015). "Association of Parkinson's Disease and Its Subtypes with Agricultural Pesticide Exposures in Men: A Case-Control Study in France." Environ. Health Perspect 123(11): 1123-1129. 5. Moisan, F., J. Spinosi, J. L. Dupupet, L. Delabre, J. L. Mazurie, M. Goldberg, E. Imbernon, C. Tzourio and A. Elbaz (2011). "The relation between type of farming and prevalence of Parkinson's disease among agricultural workers in five French districts." Movement Disord 26(2): 271-279.
Cases are selected according to consumption of anti-Parkinson's medication or long-term Parkinson's disease. Controls are randomly selected from affiliates of the same funds, matched according to age, gender and département of residence.
Nested case control|Age|Sex
Closed to new patients
Only through the study|Through links to other records or registers(drug claim databases)
Data summarised in database
Apply to PI or co-ordinator at resource
No policy exists