Name of Fellow

    Dr. Y.D. Reijmer

    Institution

    Funder

    ZonMw

    Contact information of fellow

    Country

    The Netherlands

    Title of project/programme

    ConnectAD: connecting brain injury to cognitive outcome in Alzheimer's disease

    Source of funding information

    ZonMw

    Total sum awarded (Euro)

    € 149,827

    Start date of award

    01/09/15

    Total duration of award in years

    3.0

    The project/programme is most relevant to:

    Alzheimer's disease & other dementias

    Keywords

    Alzheimer’s disease | amyloid | small vessel disease | cognition | white matter | brain connectivity | network | DTI

    Research Abstract

    The mechanisms by which Alzheimer’s disease (AD) related processes cause cognitive impairment are incompletely understood. Elucidating these mechanisms is critical to identify effective treatment strategies to prevent AD-related cognitive decline. The overall aim of the proposed work is to elucidate a potential mechanism of AD-related cognitive decline: loss of white matter connectivity. Although AD is typically characterized as a gray matter disease, the white matter is also affected, even in pre-dementia stages. Healthy white matter is crucial for efficient neuronal signaling and information flow between brain regions.

Types: Fellowships
Member States: Netherlands
Diseases: Alzheimer's disease & other dementias
Years: 2016
Database Categories: N/A
Database Tags: N/A

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