Dr Lin Hung
Determining neuronal connections involved in Parkinson's disease and cocaine addiction
Parkinson's disease & PD-related disorders
parkinson disease | addiction | substance abuse | retrograde transport | basal ganglia
Addictive behaviours in response to cocaine use and fine motor coordination that is affected in Parkinson’s disease are both controlled by the same type of cells/neurons, i.e., dopamine neurons. However, the circuitry of these neurons varies from where they originate and the type of connections they make. By understanding the neuronal circuitry of these two circuitries in concert we will be able to gain important insight into their roles in adaptive and pathological brain function.