Development of an in vivo microPET imaging platform for the non-invasive investigation of novel therapeutics in Alzheimer's disease.
Alzheimer's disease & other dementias
microPET imaging platform | novel therapeutics | Alzheimer's disease
This research project aims to improve the predictive value of preclinical animal studies through the implementation of small animal PET imaging (microPET). By employing transgenic mouse models that recapitulate certain pathological hallmarks of Alzheimer Disease we will validate and optimize a number of non-invasive biomarkers for disease monitoring.