Dr Nimeshan Geevasinga
Electrophysiological and neuroimaging evaluation of C9ORF72 related Amyotrophic lateral sclerosis
Motor neurone diseases
amyotrophic lateral sclerosis | transcranial magnetic stimulation (tms) | biomarkers | cortical excitability | neurophysiology
Amyotrophic lateral sclerosis (also known as Motor Neuron Disease) is a rapid and fatal neurological condition. To date there is no consensus on where the disease process may start. We will study healthy carriers who carry the most common ALS gene mutation and follow them over a four year period and track the associated changes. We will be using specialized neurophysiological tests to evaluate these patients and we hope to localize where the initiating problem with ALS patients may start.