Title of study

    Epidemiology and Genetics of Alzheimer? Disease

    Acronym for cohort

    Name of Principal Investigator - Title

    Prof

    Name of Principal Investigator - First name

    Vladimir

    Name of Principal Investigator - Last name

    Janout

    Address of institution -Institution

    Faculty of medicine

    Address of institution - Street address

    Syllybova 19

    Address of institution - City

    Syllybova 19

    Address of institution - Postcode

    70300

    Country

    Czech Republic

    Website
    Contact email
    Funding source

    Ministry of Health

    Q1a. Please indicate below if your cohort includes or expects to include, incidence of the following conditions?

    Alzheimer's disease and other dementias

    Q2a. In a single sentence what is the stated aim of the study? (Maximum 30 words)

    The role of risk factors in development of Alzheimer? disease

    Q2b. What distinguishes this case-control study from other studies?

    Both epidemiological and genetic data

    Q3a. i) Number of publications that involve use of your cohort to date

    15

    Q3a. ii) Please give up to three examples of studies to date (PI, Institution, Title of Study)

    Epidemiology and Genetics of Alzheimer? disease|Genetics and epidemiology of Alzheimer? disease Prof.V.Janout, Faculty of Medicine University of Ostrava|Genetics and epidemiology of mild cognitive impairment Prof.V.Janout, Faculty of Medicine Univerity of Ostrava

    Q3b. If data on research outputs are already available please paste the publication list/other data or provide a link to where these data are publicly available

    web of science

    Q3c. If no research has been done as yet, please explain in a few sentences what information (i.e. research findings) you expect will be gained from the case-control study

    Q4a. Study criteria: what is the age range of participants at recruitment? Age in years From:

    60

    Q4a. Study criteria: what is the age range of participants at recruitment? To:

    85

    Q4b. Study criteria: what are the inclusion criteria?

    no other form of dementia, minimental test less than 24

    Q4c. Study criteria: what are the exclusion criteria?

    other form of dementia , minimental test more than 24

    Q5a. What is the size of the cohort (i.e. how many participants have enrolled)?

    1,001-5,000

    Q5b. What is the expected number of control participants?

    501-1,000

    Q6a. Please describe what measures are used to characterise participants

    clinical diagnosis of Alzheimer? disease

    Q6b. Are there additional measures for participants with the clinical disorder?

    Q6c. Are there defined primary and secondary endpoints (e.g. defined health parameters)?

    No

    If YES please specify

    Q7. What is the study design?

    Prospective cohort|Genome wide association study (GWAS)|Age|Sex

    Q8. Are your cases matched by

    Cogntive function

    Q9a. Does your study includes a specialised subset of control participants?

    No

    Q9b. If your study includes a specialised subset of control participants please describe

    Q10a. Is data collection for this study

    Data analysis ongoing

    Q10b. If data collection is ongoing, are there plans to continue the cohort study beyond the current projected end date?

    Yes - funding applied for

    Q11. Are data collected

    Only through the study|Through links to medical records

    Q12. Is there a system in place to enable re-contact with patients for future studies?

    No

    Q13a. Please give information on data stored in a database (1)

    Data summarised in database

    % Available

    Q13a. Please give information on data stored in a database (2)

    No

    % Available

    Q13a. Please give information on data stored in a database (3)

    Database on spreadsheet (e.g. excel)

    % Available

    Q13a. Please give information on data stored in a database (4)

    No

    % Available

    Q13a. Please give information on data stored in a database (5)

    No

    % Available

    Please specify language used

    % Available

    Q13b. Please give information on how data is held as individual records

    No

    % Available

    Q14a. Are data available to other groups?

    No

    Q14b. If data is available to other groups what is the access policy/mechanisms for access?

    Q15. What data sharing policy is specified as a condition of use?

    No policy exists

    Q16a. Are tissues/samples/DNA available to other groups?

    Yes

    Q16b i) If yes, please describe below

    Living donors: DNA

    Q16b. ii) In what form are tissues/samples/DNA supplied?

    Primary Samples: Stabilised samples (frozen or fixed)

    Q16b iii) Is the access policy/mechanism for obtaining samples the same as that for obtaining data (Q14 above)?

    No

    Q17. Is information on biological characteristics available to other groups?

    No

Types: Case Control Studies
Member States: Czech Republic
Diseases: Alzheimer's disease & other dementias
Years: 2016
Database Categories: N/A
Database Tags: N/A

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