Title of project or programme

Excellence Cluster: Regenerative Therapies: From Cells to Tissues to Therapies: Engineering the Cellular Basis of Regeneration

Principal Investigators of project/programme grant
Title Forname Surname Institution Country
Prof. Michael Brand Technical University Dresden, Center for Generative Therapies in Dresden Germany
 Prof.  Martin Technical University Dresden  Germany
 Prof.  Petra  Schwille Technical University Dresden  Germany
 Prof.  Wieland  Huttner MPI for Molecular Cell Biology and Genetics, Dresden  Germany
Address of institution of lead PI
Institution Technical University Dresden, Center for Regenerative Therapies, Dresden
Street Address Am Tatzberg 47/49
City Dresden
Postcode 01307
Country

Germany

Source of funding information

Deutsche Forschungsgemeinschaft

Total sum awarded (Euro)

10000000

Start date of award

01-11-2006

Total duration of award in months

132

The project/programme is most relevant to
  • Alzheimer’s disease and other dementias
  • Parkinson’s disease
  • Neurodegenerative disease in general
Keywords
Research abstract in English

“An important goal of biomedical research for the 21st century is to understand how to exploit the regenerative capacity of the body for new therapies. Reconstructive therapy is already a reality for the transplantation of haematopoetic stem cells. However, for many major diseases such as diabetes, Morbus Parkinson, Alzheimer, bone/cartilage or myocardial diseases, regenerative therapy is still fiction. The Center for Regenerative Therapies Dresden (CRTD) integrates research in the field of nanotechnology, material science, medicine and biology in order to develope novel strategies for regenerative therapies. Our main objectives are: (1) to develop advanced regenerative therapies for haemato-oncological, endocrine, neurodegenerative, bone/cartilage and cardiovascular diseases, (2) to study the crucial mechanisms controlling stem cell recruitment, activation, proliferation, and differentiation, in model organisms, (3) to control these cellular processes using genetics, surface engineering, matrix engineering and microdevices in order to provide control of stem cell activity and regeneration, (4) to test the novel regeneration therapies in pre-clinical and clinical trials, (5) to develop such therapies into marketable products with our commercial partners, (6) to develop a leading center for Regenerative Therapies in Europe. The CRTD uses the financial support (cluster of excellence award) by the DFG to: (1) catalyse the clinical translation of basic research results by creating dedicated clinical research positions, (2) boost the application of new technologies in clinical and preclinical research through joint project funding, improved technology and facilitated technology transfer, (3) strengthen materials sciences approaches by setting up a dedicated professorship in this area, (4) create novel career options for junior researchers and support for female scientists.”

Lay summary

Types: Investments > €500k
Member States: Germany
Diseases: Alzheimer's disease & other dementias, Neurodegenerative disease in general, Parkinson's disease & PD-related disorders
Years: 2011
Database Categories: N/A
Database Tags: N/A

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