Dr Leonardo Gollo
From brain maps to mechanisms: Modelling the pathophysiology of dementia
Alzheimer's disease & other dementias
dementia | alzheimer disease | computer simulation | brain disease | brain ageing
As the brain ages, the relationship between its structure and function also changes. In this study, I will use detailed computational modelling and extensive analyses of brain dynamics to improve interventional strategies by: 1. Characterising healthy and unhealthy brain dynamics during ageing; 2. Classifying the various subtypes of pathological dynamics; and 3. Predicting pathological neurodegeneration by identifying the earliest signs of perturbations in healthy ageing.