Name of Fellow

    Myllykangas Liisa

    Institution

    Funder

    Academy of Finland

    Contact information of fellow

    Country

    Finland

    Title of project/programme

    GENETIC AND NEUROPATHOLOGICAL CHARACTERIZATION OF NEURODEGENERATIVE DISEASES

    Source of funding information

    Academy of Finland

    Total sum awarded (Euro)

    € 285,181

    Start date of award

    01/09/16

    Total duration of award in years

    4.0

    The project/programme is most relevant to:

    Neurodegenerative disease in general

    Keywords

    Neurogeneration | genetics | neuropathology | risk factor | familial | GWAS | GWS | Alzheimer's disease | Dementia with Lewy bodies | frontotemporal dementia

    Research Abstract

    Neurodegenerative diseases, such as Alzheimer’s disease and dementia with Lewy bodies, are the most common causes of dementia, a major health problem in Western countries. The majority of patients (> 90%) suffer from the common, multifactorial disease forms, but many rare familial forms, caused by inherited single-gene defects, are also known. In this project, we aim to 1) identify genetic factors that predispose to the common forms of neurodegenerative disorders at the population level and 2) gene defects that cause rare familial disease forms. Furthermore, the effect of the genetic factors on tissue level is being studied in brain sections of the patients. The study is expected to identify key molecules and mechanisms involved in the development of neurodegenerative diseases. This may enable the development of diagnostics, treatment and prevention of neurodegenerative disorders.

Types: Fellowships
Member States: Finland
Diseases: Neurodegenerative disease in general
Years: 2016
Database Categories: N/A
Database Tags: N/A

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