Dr Peter Crouch
University of Melbourne
Harnessing the consequences of impaired mitochondrial energy metabolism to treat the symptoms of age-related neuronal decline
National Health and Medical Research Council
Cognitive function and locomotor ability decline due to advanced age and disorders such as motor neuron disease, Alzheimers and Parkinsons disease. We have identified a treatment that attenuates these symptoms of age and disease in mice, thus extending the healthy lifespan of the animals. This project will investigate the mechanisms by which the treatment works, thereby advancing our understanding of the causes of cognitive and locomotor decline and the development of preventative treatments.