Dr Peter Crouch
Harnessing the consequences of impaired mitochondrial function to treat and image motor neuron disease
Motor neurone diseases
amyotrophic lateral sclerosis | motor neuron disease (mnd) | mitochondria | therapeutics | neurodegenerative disorders
Motor neuron disease (MND) is a group of fatal adult-onset diseases affecting the neurons that relay signals from the brain to muscles. The incidence of MND is rapidly increasing due to the ageing population and a diagnosis of MND comes with a prognosis of paralysis and 2-5 years survival. The diagnosis process is lengthy, and even after MND is confirmed, there are no effective therapeutics. This research project aims to develop new therapeutic and diagnostic options for MND.