Principal Investigators
Prof Andrew Hill
Institution
La Trobe University
Contact information of lead PI
Country
Australia
Title of project or programme
How do small extracellular vesicles contribute to the development of prion disease
Source of funding information
National Health and Medical Research Council
Total sum awarded (Euro)
390,993
Start date of award
01/01/2013
Total duration of award in years
4
Keywords
Research Abstract
Prion diseases are transmissible neurodegenerative disorders associated with the misfolding of the prion protein. This proposal will investigate how cells release the infectious agent responsible for prion diseases in small nanovesicles known as exosomes. We will characterise the novel processed forms of the proteins involved in these two neurodegenerative diseases within the exosomes and investigate whether the genetic content of exosomes has diagnostic potential.
Further information available at:
Types: Investments < €500k
Member States: Australia
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A