Dr Andrew Watt
In vivo assessment of the role of aggregated tau in preclinical and prodromal Alzheimer's disease
Alzheimer's disease & other dementias
alzheimer disease | amyloid beta-protein | neurofibrillary tangles | positron emission tomography (pet) | diagnostic imaging
Subtle changes in the brain precede an Alzheimers disease (AD) diagnosis by 20-30 years. These changes provide an incredible opportunity to diagnose and treat AD; however, our understanding of them, remains limited. We aim to use new imaging technologies to investigate these subtle changes in the preclinical AD brain. This will give us a greater understanding of how these early changes effect AD progression and whether we can use this information to improve the diagnosis and treatment of AD.