Dr Adam Walker
Investigating mechanisms of dementia and motor neuron disease
Alzheimer's disease & other dementias
amyotrophic lateral sclerosis | dementia | protein aggregation | motor neuron disease (mnd) | cell biology
Dementia and motor neuron disease (MND) are both neurodegenerative diseases which have devastating impacts on patients and their families. My research investigates the biochemical mechanisms involved in these diseases. Pathology in the nervous system of dementia and MND patients contains a protein called TDP-43, but it remains unknown how this causes disease. This project will therefore explore the effects of TDP-43 malfunction, which will provide insight into potential therapeutic strategies.