Dr Scott Ayton
University of Melbourne
Investigating the cause and consequences of iron deposition in Parkinson's disease
National Health and Medical Research Council
It is known that iron elevation occurs in the brain in Parkinsons disease. This might cause cell death by rusting. It is not known (1) how iron accumulates in the disease, (2) whether iron accumulation contributes to the worsening of the disease and (3) if lowering iron with a drug would improve symptoms. We plan to address these questions using a clinical cohort of patients, and laboratory animal models.