Name of Fellow

    Dr. P.J.W. Naudé

    Institution

    Funder

    ZonMW | Alzheimer Nederland | Neurosearch Antwerp.

    Contact information of fellow

    Country

    The Netherlands

    Title of project/programme

    Lipocalin 2 and its receptor, megalin, as diagnostic and drug targets in early stages of Alzheimer’s disease.

    Source of funding information

    ZonMW | Alzheimer Nederland | Neurosearch Antwerp.

    Total sum awarded (Euro)

    € 150,000

    Start date of award

    01/11/15

    Total duration of award in years

    3.0

    The project/programme is most relevant to:

    Alzheimer's disease & other dementias

    Keywords

    Neuroinflammation | diagnostic markers | therapeutic target | mild cognitive impairment | Lipocalin 2 | Megalin | early Alzheimer’s disease

    Research Abstract

    Lipocalin 2 (Lcn2) is a newly identified (neuro)inflammatory component that, together with its receptor, megalin, can play important roles in the pathophysiology of Alzheimer’s disease (AD) development. This project will investigate Lcn2 and megalin as novel diagnostic and therapeutic targets for early AD, addressing two fundamental research topics in this field: i.e. early diagnosis and early intervention, aiming to prevent AD development or at least stop or slow down disease progression.

Types: Fellowships
Member States: Netherlands
Diseases: Alzheimer's disease & other dementias
Years: 2016
Database Categories: N/A
Database Tags: N/A

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