A/Pr Clement Loy
Longitudinal transcriptome profiles for people with dementia
Alzheimer's disease & other dementias
dementia | alzheimer disease | huntington's disease | rna | neurogenetics
Over the past decade, less than half a percent of drugs trialled for Alzheimer Disease were found to be effective. This highlights the need for new drug targets. This Fellowship aims to study how genes express themselves over time, among people with very high risk of dementia (genetic form of Alzheimer Disease and Huntington Disease). By looking at gene expression in nerve tissue in the nose, fluid around the brain, and blood, I hope to better understand the disease mechanisms causing dementia.