Principal Investigators


Ka?ovský Petr Prof. MUDr. CSc.

Institution


Faculty Hospital Olomouc

Contact information of lead PI


Country


Czech Republic

Title of project or programme


Markers of neurodegeneration in differential diagnosis of parkinsonian syndrome

Source of funding information


Ministry of Health of the Czech Republic

Total sum awarded (Euro)


€ 201,000

Start date of award


01/06/2011

Total duration of award in years


5

Keywords


Research Abstract


Parkinson syndrome (PS) is characterised by bradykinesis, rest tremor, rigidity and postural instability. The most frequent cause (about 80%) is idiopatic Parkinson’s disease. But also a number of other neurodegenerative diseases , e.g. Lewy body disease, progressive supranuclear palsy, multisystem atrophy, corticobasal degeneration etc., can manifest itself with PS. Differential diagnosis between individual diseases is highly limited. Project goal will be in case of patients with PS and age identical control group to do detailed examination of serum and cerebrospinal fluid with determination of levels of neurodegenerative markers, inflamattory markers, oncomarkers, histic destruction pointers and other. The levels of the markers we took will be from now on compared with the disease process, its possible progression or development in different diseases. Gathered information could be instrumental towards the asessment of possible predictive factor defining disease prediction.

Further information available at:

Export as PDF