Molecular PET imaging of Tau in comparison with AD and non-AD dementia pathology
The Swedish Brain Foundation
Differential diagnosis among the different causes of dementia should be as accurate as possible in order to benefit from specific drug /non-drug intervention. AD is the most common
form of neurodegenerative and dementia disorder characterized by initially subtle episodic memory problem followed by gradual loss of cognitive functions and loss of independency. It is characterized by complex neuropathology where dysfunction in brain of processing, deposition
and clearance of beta amyloid (Aß) together with deposition of neurofibrillary tangles as well as inflammatory processes lead to synaptic dysfunction. This application has a focus on
several of these pathological processes for new imaging biomarker development.