New biomarkers of motor neuron disease: role in the pathogenesis and possible therapeutic targets
|Valentia||Banetto||Istituto di Ricerche Farmacologiche Mario Negri||Italy|
|Institution||Istituto di Ricerche Farmacologiche Mario Negri|
|Street Address||Via La Masa 19|
- Motor neurone diseases
Evaluation of the capability of potential biomarkers to deliver a right diagnosis of the motor neuron disease (MND) and their use as potential therapeutic targets. Particularly, a biomarker either in patients and in animal models, cyclophillin A, seems to be involved in the process that leads to death of the motor neuron. Further studies on this field could bring to the development of new and effective therapeutic approaches.