Title of project or programme

New biomarkers of motor neuron disease: role in the pathogenesis and possible therapeutic targets

Principal Investigators of project/programme grant
Title Forname Surname Institution Country
Valentia Banetto Istituto di Ricerche Farmacologiche Mario Negri Italy
Address of institution of lead PI
Institution Istituto di Ricerche Farmacologiche Mario Negri
Street Address Via La Masa 19
City Milan
Postcode 20156
  • Italy
Source of funding information

Telethon Foundation

Total sum awarded (Euro)


Start date of award


Total duration of award in months


The project/programme is most relevant to
  • Motor neurone diseases
Research abstract in English
Lay summary

Evaluation of the capability of potential biomarkers to deliver a right diagnosis of the motor neuron disease (MND) and their use as potential therapeutic targets. Particularly, a biomarker either in patients and in animal models, cyclophillin A, seems to be involved in the process that leads to death of the motor neuron. Further studies on this field could bring to the development of new and effective therapeutic approaches.

Types: Investments > €500k
Member States: Italy
Diseases: Motor neurone diseases
Years: 2011
Database Categories: N/A
Database Tags: N/A

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