Newcastle 85+ Study
Newcastle 85+ Study
|Institution||Newcastle University Institute for Ageing and Health|
|Street Address||Campus for Ageing and Vitality|
|City||Newcastle upon Tyne|
Medical research council
- Alzheimer’s disease and other dementias
- Parkinson’s disease
- Neurodegenerative disease in general
To investigate in great detail the clinical, biological and psychosocial factors associated with ageing among a fully representative cohort all born in 1921 and aged 85 at entry.
High recruitment rate (72%) from target population including those living in institutions and with cognitive impairment. Very extensive multi-dimensional health assessment including a wide range of functional tests and assesments, blood-based biomarkers, activity monitoring and questionnaires, as well as review of GP records.
Kirkwood, Newcastle University Institute for Ageing and Health, Health and disease in 85 year olds
Adamson, Newcastle University Institute of Health and Society, Dietary assessment in the Newcastle 85+ study
Jagger, Newcastle University Institute for Ageing and Health, Projections of future care needs
Collerton J, Barrass K, Bond J, Eccles M, Jagger C, James OFW, Martin-Ruiz C, Robinson AL, von Zglinicki T, Kirkwood TBL. The Newcastle 85+ study: biological clinical and psychosocial factors associated with healthy ageing: study protocol. BMC Geriatrics. 2007;7:14.
Collerton J, Collerton D, Arai Y, Barrass K, Eccles M, Jagger C, McKeith IG, Saxby BK, Kirkwood TBL. A comparison of the acceptability, feasibility and utility of computerised and pencil and paper tasks in assessing cognitive function in community dwelling older people in the Newcastle 85+ Pilot Study. Journal American Geriatric Psychiatry 2007;55:1630-1635.
Collerton JC, Martin-Ruiz C, Kenny A, Barrass K, Von Zglinicki T, Kirkwood TBL, et al. Telomere length is associated with left ventricular function in the oldest old: the Newcastle 85+ study. European Heart Journal 2007;28:172-176.
Adamson AJ, Collerton J, Davies K, Foster E, Jagger C, Stamp E, Mathers JC, Kirkwood TBL; Newcastle 85+ Study Core Team. Nutrition in advanced age: dietary assessment in the Newcastle 85+ study. Eur J Clin Nutr. 2009;63:S6-18.
Collerton J, Davies K, Jagger C, Kingston A, Bond J, Eccles MP, Robinson LA, Martin-Ruiz C, von Zglinicki T, James OF, Kirkwood TBL. Health and disease in 85 year olds: baseline findings from the Newcastle 85+ cohort study. BMJ. 2009;339:b4904.
Jagger C, Collerton JC, Davies K, Kingston A, Robinson LA, Eccles MP, von Zglinicki T, Martin-Ruiz C, James OF, Kirkwood TBL, Bond J. Capability and dependency in the Newcastle 85+ cohort study. Projections of future care needs. BMC Geriatrics 2011;11:21.
|Age in years from:||85|
|To (‘until death’ if applicable):||86|
Resident in Newcastle or North Tyneside and registered there with a GP.
Born in 1921
None other than exclusion by GP as being in last stages of terminal illness or as posing a potential safety risk to a visiting member of the research team.
1,000 – 5,000 participants
- Prospective cohort
- Data collection ongoing
- Data analysis ongoing
- Closed to new patients
- Yes – funding applied for
- Only through the study
Yes (participants have given permission to be re-contacted via the PIs to ask if they would participate in further studies)
|Data summarised in database||Yes||85%|
|Database is web-based|
|Database on spreadsheet||Yes||85%|
|Database is on paper|
|Data held as individual records|
|Data is web-based|
|Data held on computer based records||Yes||85%|
|Data held on cards|
- Apply to PI or co-ordinator at resource
- Access Committee mechanism
No requirement to make data publicly available
- Living donors: blood derivatives
- Living donors: DNA
- Secondary samples: plasma
- Secondary samples: DNA
- Yes, for all the cohort