Title of cohort

    Quebec Longitudinal Study on Nutrition and Successful Aging

    Acronym for cohort

    NuAge

    Name of Principal Investigator - Title

    Prof

    Name of Principal Investigator - First name

    Hélène

    Name of Principal Investigator - Last name

    Payette

    Address of institution -Institution

    Centre de recherche sur le vieillissement

    Address of institution - Street address

    1036, rue Belvédère Sud

    Address of institution - City

    Sherbrooke

    Address of institution - Postcode

    J1H 4C4

    Country

    Canada

    Funding source

    CIHR and the Quebec network for Research on aging

    Q1a. Please indicate below if your cohort includes or expects to include, incidence of the following conditions?

    Alzheimer's disease and other dementias

    Q1b. When are studies on the above condition(s) expected to become possible?

    Already possible

    Q2a. In a single sentence what is the stated aim of the cohort?

    Impact of Nutrition of cognitive decline and AD

    Q2b. What distinguishes this cohort from other population cohorts?

    Extensive data on nutrition, functional capacity, antropometry, gene polymorphism and serum biomarkers; biobank of serum, plasma, urine, saliva, DNA and RNA

    Q3a. i) Number of publications that involve use of your cohort to date

    45

    Q3a.ii) Please give up to three examples of studies to date (Principal Investigator, Institution, Title of Study)

    Q3b. If data on research outputs are already available please paste the publication list/other data or provide a link to where these data are publicly available

    https://www.ncbi.nlm.nih.gov/pubmed/?term=NuAge+study

    Q3c. If no research has been done as yet, please explain in a few sentences what information (i.e. research findings) you expect will be gained from the population

    Q4a. Study criteria: what is the age range of participants at recruitment? Age in years From:

    68

    Q4a. Study criteria: what is the age range of participants at recruitment? To:

    82

    Q4b. Study criteria: what are the inclusion criteria?

    PMID: 17708689

    Q4c. Study criteria: what are the exclusion criteria?

    PMID: 17708689

    Q5. What is the size of the cohort (i.e. how many participants have enrolled)?

    1,000-5,000 participants

    Q6a. Please describe what measures are used to characterise participants

    PMID: 17708689

    Q6b. Are there additional measures for participants with a clinical disorder?

    Specific cognitive domains

    Q6c. Are there defined primary and secondary endpoints (e.g. defined health parameters)?

    If yes please specify

    Q7. What is the study design (select all that apply)?

    Longitudinal| Prospective cohort

    Q8. Are your cases matched by

    Q9a. Does your study include a specialised subset of control participants?

    No

    Q9b. If your study includes a specialised subset of control participants please describe

    Q10a. i) Please enter the data collection start date

    12/01/2003

    Q10a. ii) Please enter the data collection end date

    12/2009 + telelphoen interviews 2014-2015

    Q10a. iii) Is data collection for this study

    Data analysis ongoing

    Q10b. If data collection is ongoing, are there plans to continue the cohort study beyond the current projected end date?

    Q11. Is data collected

    Only through the study

    Other please specify here

    Q12. Is there a system in place to enable re-contact with patients to ask about participation in future studies?

    Yes (participants given permission to be re-contacted via PIs)

    Q13a. Please give information on the format and availability of data stored in a database (1)

    Data summarised in database

    % available

    100

    Q13a. Please give information on the format and availability of data stored in a database (2)

    No

    % available

    Q13a. Please give information on the format and availability of data stored in a database (3)

    No

    % available

    Q13a. Please give information on the format and availability of data stored in a database (4)

    No

    % available

    Other (please specify)

    % available

    Q13b. Please give information on the format and availability of data held as individual records (1)

    Data is held as individual records

    % available

    100

    Q13b. Please give information on the format and availability of data held as individual records (2)

    No

    % available

    Q13b. Please give information on the format and availability of data held as individual records (3)

    Data held on computer based records

    % available

    100

    Q13b. Please give information on the format and availability of data held as individual records (4)

    No

    % available

    Please specify language used

    French and English

    Q14a. Is data available to other groups?

    Yes

    Q14b. If data is available to other groups what is the access policy/mechanisms for access?

    Apply to PI or co-ordinator at resource| Access committee mechanism|Local/ regional access| National Access| International Access| Access for pilot studies permitted| Applicant needs to provide separate external ethics approval| Proposal review

    Q15. What data sharing policy is specified as a condition of use?

    Q16a. Are tissues/samples/DNA available to other groups?

    Yes

    Q16b i) If yes, please describe below:

    Living donors: blood derivatives| Living donors: DNA| Other (saliva, urin)

    Q16b. ii) In what form are tissues/samples/DNA supplied?

    Primary Samples: Stabilised samples (frozen or fixed)| Secondary samples: plasma| Secondary samples: DNA| Secondary samples: RNA

    Q16b. iii) Is the access policy/mechanism for obtaining samples the same as that for obtaining data (Q14 above)?

    Yes

    Q17. Is information on biological characteristics available to other groups?

    If available for a subset please specify number of patients and % of total cohort

    Number of Patients

    1300-1600

    % of total cohort

    75-90

Types: Population Cohorts
Member States: Canada
Diseases: Alzheimer's disease & other dementias
Years: 2016
Database Categories: N/A
Database Tags: N/A

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