Principal Investigators
Gauchat, Jean-François M
Institution
Université de Montréal
Contact information of lead PI
Country
Canada
Title of project or programme
Roles of cardiotrophin-like cytokine partners in the immune response
Source of funding information
CIHR
Total sum awarded (Euro)
469,967
Start date of award
01/10/2013
Total duration of award in years
5
Keywords
Research Abstract
The phenotypes of patients deficient for the gene coding for cardiotrophin-like cytokine (CLC) indicate that this protein has multiple roles in the nervous and immune systems, suggesting that it interacts with multiple partners. We identified two of these partners that could have key roles in autoimmune and Alzheimer diseases. We will investigate the immunoregulatory roles of CLC complexed with these molecules and their functions in models of multiple sclerosis and Alzheimer diseases.
Further information available at:
Types: Investments < €500k
Member States: Canada
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A