Prof Perminder Sachdev
University of New South Wales
The genetic and environmental determinants of amyloid deposition in older individuals: an amyloid imaging study using the twin design
National Health and Medical Research Council
Alzheimers disease is characterised by the deposition of amyloid plaques in the brain. We dont fully understand how amyloid deposition occurs and what contribution is made by genetic and environmental factors. Amyloid deposition in the brain can now be quantified during life using positron emission tomography. In this study, we will examine brain amyloid in twins, which will determine what proportion of the pathology is attributable to environmental factors that may be modifiable.