Title of project or programme

Theurapeutic and preventative impact of nutritional lipids on neuronal and cognitive performance in aging, Alzheimer’s disease and vascular dementia (LIPIDIDIET)

Principal Investigators of project/programme grant
Title Forname Surname Institution Country
Professor Tobias Hartmann UNIVERSITAET DES SAARLANDES Germany
Address of institution of lead PI
Institution UNIVERSITAET DES SAARLANDES
Street Address
City
Postcode
Country

Germany

Source of funding information

European Commission

Total sum awarded (Euro)

5899843

Start date of award

01-08-2008

Total duration of award in months

60

The project/programme is most relevant to
  • Alzheimer’s disease and other dementias
Keywords

Diet,Food,Aging,Nutrition,Alzheimer’s Disease,DHA,Cholesterol

Research abstract in English

It is our aim to develop a lipid based diet that is able to delay or prevent onset of Alzheimer’s disease and related diseases and has a stabilizing effect on cognitive performance in aging. Multiple lines of evidence suggest that there is a large overlap between risk factor of these three diseases. Importantly, there is equally strong evidence that prevention and treatment of these diseases can be efficiently addresses – especially in their first and their priclinical stages – by closely related or identical bio-molecules. Predominantly these molecules appear to belong to the class of lipids which are part of the human diet. However, very often they are consumed in far lesser than recommended amounts. Bearing in mind that all of these diseases have a long pre-clinical phase in which the disease remains undetected specifically designed nutrition may be requirred for effective prevention or for those who already progressed into the first clinical stage of the disease. Moreover, frequently the within the elderly population pathological changes by two or all of these diseases occur in combination thus targeting only one would be insufficient. Taking these aspects into consideration, dietary supplementation, composed to maximize benefit for all three of these in the elderly common diseases, appears to be the most suitable approach to provide a general health perspective improvement for this age group in the EU population.

Lay summary

Types: Investments > €500k
Member States: Germany
Diseases: Alzheimer's disease & other dementias
Years: 2011
Database Categories: N/A
Database Tags: N/A

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