Dr Rachel Buckley
What can tau deposition tell us about the appearance of subjective and objective cognitive decline in older adults?
Alzheimer's disease & other dementias
cognitive decline | imaging | older people | early detection | dementia-related decline in memory
Subjective memory concerns are common in older adults, but it is uncertain how they relate to Alzheimers disease (AD) biomarkers. Novel neuroimaging techniques have been developed for measuring tau deposition, a hallmark feature of AD. Using this technique, I aim to determine whether tau is sensitive to certain types of subjective concerns. My findings will reveal which concerns are indicative of AD risk, and which arise from unrelated factors, such as inattention or stress.