Tag Archives: cross-disease

Neurobiology of Disease“The choroid plexus in health and in disease: Dialogues into and out of the brain” has been published in Neurobiology of Disease. This research was supported in part by JPND through the NeuroGem project, selected under the 2013 cross-disease analysis call, and PROP-AD, selected under the 2015 JPco-fuND call.

 

Nature Communications“Laser capture microscopy coupled with Smart-seq2 for precise spatial transcriptomic profiling” has been published in Nature Communications. This research was supported in part by JPND through the DAMNDPATHS project, selected under the 2013 cross-disease analysis call.

Cell Reports“Presenilin 2 Modulates Endoplasmic Reticulum-Mitochondria Coupling by Tuning the Antagonistic Effect of Mitofusin 2” has been published in Cell Reports. This research was supported in part by JPND through the CeBioND project, which was selected in the 2013 call for research projects for the cross-disease analysis of pathways related to neurodegenerative diseases.

NeuronUnderstanding Dopaminergic Cell Death Pathways in Parkinson Disease” has been published in Neuron. This research was supported in part by JPND through the CrossSeeds project, selected in the 2013 call for research projects for cross-disease analysis of pathways related to neurodegenerative diseases, and the SYNaction project, selected under the 2015 JPco-fuND call.

“Conversion of Synthetic Aβ to In Vivo Active Seeds and Amyloid Plaque Formation in a Hippocampal Slice Culture Model” has been published in The Journal of Neuroscience. This research was supported in part by JPND through the NeuTARGETs project, which was selected for support in the 2013 call for research projects for cross-disease analysis of pathways related to neurodegenerative diseases.

Criteria for folding in structure-based models of proteins” has been published in The Journal of Chemical Physics. This research was supported in part by JPND through the MisingLink project, selected in the 2013 cross-disease analysis call.

A new paper titled “Structural and functional properties of prefibrillar α-synuclein oligomers” has been published in Scientific Reports. It was partly funded by JPND through the NeuTARGETs project, which was selected for support in the 2013 call for research projects for cross-disease analysis of pathways related to neurodegenerative diseases.

Marisol Touraine, Minister of Social Affairs, Health and Women’s Rights, Geneviève Fioraso, State Secretary for Higher Education and Research, and Laurence Rossignol, Secretary of State for Families, People elderly and Autonomy, recently launched the French National Plan neurodegenerative diseases 2014-2019.

Announced by the President of the Republic, this plan from a wide consultation with stakeholders, has three priorities:

  • Improving the diagnosis and management of patients
  • Ensuring the quality of life of patients and their caregivers
  • Develop and coordinate research

The French Government is committed to a dynamic of progress in research, care and support. The plan takes into account the specificities of each disease and provides concrete solutions to the needs of patients and their caregivers.

A total of fifteen international consortia have been proposed for funding under two JPND Transnational calls between a total of 18 countries.

These new projects are aiming to analyse neurodegenerative diseases across traditional clinical boundaries, and also to begin “pilot” studies for the design of preventive strategies.

The projects are supported under two JPND transnational calls for proposals entitled:

The calls were launched in December 2013 with a pre-proposal deadline of March 2014. Sixteen countries participated in each call.

The project proposals have been proposed for funding by the respective Peer Review Panels based on scientific evaluation and by the respective Call Steering Committees based on budget availability.

For further information on the projects proposed for funding, click on the links below.